Use of botuline toxin to obtain a product to be used in articular pathologies, particularly coxarthrosis, epicondylitis and rotator muscle cap pathology
AssigneeSociete de Conseils de Recherches et d'Applications Scientifiques
InventorsCorrado Marchini, Fabiano Pinat, Fabio Pinat, Francesca Zecchini
Life of this patent
Estimating the term…
Abstract
Use of botulin toxin to obtain a product intended to he administered intramuscular with lissive effect in treating articular pathologies, particularly coxarthrosis, or arthrosis of the hip, epicondylitis of the elbow and rotator muscle cap pathology of the shoulder.
Claims12
1- Use of botulin toxin to obtain a product intended to be administered intramuscular with lissive effect in treating articular pathologies, particularly coxarthrosis, or arthrosis of the hip, epicondylitis of the elbow and rotator muscle cap pathology of the shoulder.
2- Use as in claim 1, characterized in that to obtain the product to be administered botulin toxin is selected from the group comprising the sub-types A, B, C, D, E, F and G.
3- Use as in claim 1 or 2, characterized in that the product provides as a basic dose a quantity of botulin toxin which, as an example using Dysport type A, is comprised between 25 and 100 MU, advantageously 50 MU.
4- Use as in any claim hereinbefore, characterized in that the product for use can include several basic doses, or several products having a basic dose can be used simultaneously.
5- Use as in any claim hereinbefore, characterized in that the product also comprises human albumin in cooperation with the botulin toxin.
6- Use as in any claim from 1 to 5 inclusive, characterized in that the product also comprises at least lactose in cooperation with the botulin toxin.
7- Use as in any claim from 1 to 5 inclusive, characterized in that the product also comprises at least a sodium-based compound in cooperation with the botulin toxin.
8- Use as in any claim hereinbefore, characterized in that the product comprises a physiological solution containing sodium chloride between g 0.45% and 1.0%, advantageously 0.9%.
9- Use as in any claim hereinbefore, characterized in that, in the event it is used for coxarthrosis, the product is administered into the thigh muscles affected, such as in particular the great adductor, the long adductor, the ileopsoas or the tensor of the fascia lata.
10- Use as in any claim hereinbefore, characterized in that, in the event it is used for epicondylitis, the product is administered into the epicondyloid muscles affected, such as the anconeus, the common extensor of the fingers, the extensor of the little finger, the ulnar extensor of the wrist, in order to reduce the tension in the tendinous insertion seat of said muscles.
11- Use as in any claim hereinbefore, characterized in that, in the event it is used for rotator muscle cap pathology, the product is administered into the rotator muscles affected, such as the supraspinal, the infraspinal, the subspinal and the teres minor.
12- Use as in any claim hereinbefore, characterized in that the intra-muscular administration of the product is associated with the use of an electromyographic guide.