Intraluminal needle injection substance delivery system with filtering capability

A delivery system for administering therapeutic drugs or substances in a body vessel of a patient, comprising:

• a delivery catheter having a proximal end and a distal end and a delivery lumen for receiving the cannula of a syringe and a guide wire lumen for receiving a guide wire, the delivery lumen having a distal end through which the cannula extends for the administration of a therapeutic drug or substance to the body vessel;
• a filtering device associated with the drug delivery catheter for capturing particles which may be entrained in the body fluid passing through the body vessel;
• a guide wire disposed within the guide wire lumen;
• and
• a delivery sheath adapted to extend co-axially over the delivery catheter and the filtering device when the delivery system is being advanced within the body vessels of the patient.

A method for administering therapeutic drugs or substances intraluminally in a body vessel of a patient, comprising:

• providing a delivery system including a delivery catheter having a proximal end and a distal end and a delivery lumen for receiving the cannula of a drug delivery device, the delivery lumen having a distal end through which a cannula extends for the administration of a therapeutic drug or substance to the body vessel and an filtering device associated with the delivery catheter for capturing unwanted particles which may be entrained in the body fluid passing through the body vessel;
• advancing the delivery catheter intraluminally through the patient to position the end of the delivery lumen near or in contact with the location of the body vessel where the drug or substance is to be administered;
• deploying the filtering device within the body vessel;
• advancing the cannula of a drug delivery device through the delivery lumen placing the end of the cannula near or into the body vessel;
• and
• administering the drug or substance to the body vessel.