US 2004/0063115 A1Published application

Enzymes

OwnerY Tom Tang, Jennifer A. Griffin +17inventors

InventorsY Tom Tang, Jennifer A. Griffin, Henry Yue, Ernestine A. Lee, Mariah R. Baughn, Brendan M. Duggan, Narinder K. Walia, Sally Lee, Jayalaxmi Ramkumar, Bridget A. Warren, Ammena R. Gandhi, Dyung Aina M. Lu, Yan Lu, Monique G. Yao, Li Ding, Catherine M. Tribouley, Madhusudan M. Sanjanwala, Chandra S. Arvizu, Jennifer L. Jackson

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Abstract

The invention provides human enzymes (NZMS) and polynucleotides which identify and encode NZMS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NZMS.

Claims91

Dependent claims

An isolated polypeptide selected from the group consisting of:

a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-18,
b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1-17,
c) a polypeptide comprising a naturally occurring amino acid sequence at least 94% identical to the amino acid sequence of SEQ ID NO:18,
d) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-18, and
e) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-18.

2 more elements

Dependencies are inferred from the claim text.