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US 2004/0062813 A1Published application
Transdermal drug delivery devices having coated microprotrusions
OwnerMichel J. N. Cormier, Wendy A. Young +3inventors
InventorsMichel J. N. Cormier, Wendy A. Young, Juanita A. Johnson, Peter E. Daddona, Mahmoud Ameri
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Abstract
Methods are provided for preparation of a coating on one or more microprojections of a microprojection array using wetting agents either as a pretreatment of the microprojection surfaces or incorporated in the coating formulation along with the active agent.
Claims23
A method of coating the surface of one or more microprojections of a microprojection array comprising the steps of:
- providing a microprojection array comprised of one or more microprojections;
- treating the surface of one or more of said microprojections of said microprojection array with a method selected from group consisting of chemical pre-etching, plasma treatment, heat treating, rinsing with an alkaline detergent and rinsing with a wetting agent;
- providing a coating formulation comprising an active agent;
- applying said coating formulation to said treated surfaces of said one or more microprojections;
- and
- drying said coating formulation onto said surfaces to form a coating.
3 more elements
A method of coating the surface of one or more microprojections of a microprojection array comprising the steps of:
- providing a microprojection array comprised of one or more microprojections;
- providing a coating formulation comprising an active agent and a wetting agent;
- applying said coating formulation to said surfaces of said one or more microprojections;
- and
- drying said coating formulation onto said surfaces to form a coating.
2 more elements
Dependencies are inferred from the claim text.