US 2004/0029136 A1Published application

Lipid metabolism molecules

OwnerY. Tom Tang, Yalda Azimzai +17inventors

InventorsY. Tom Tang, Yalda Azimzai, Debopriya Das, Michael B. Thornton, Dyung Aina M. Lu, Catherine M. Tribouley, Henry Yue, Ammena R. Gandhi, Narinder K. Chawla, Farrah A. Khan, Yan Lu, Monique G. Yao, April J.A. Hafalia, Vicki S. Elliott, Chandra S. Arvizu, Preeti G. Lal, Jayalaxmi Ramkumar, Danniel B. Nguyen, Mariah R. Baughn

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Abstract

The invention provides human lipid metabolism molecules (LMM) and polynucleotides which identify and encode LMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LMM.

Claims60

Dependent claims

An isolated polypeptide selected from the group consisting of:

a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-8,
b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1-3 and SEQ ID NO:5-8,
c) a polypeptide comprising a naturally occurring amino acid sequence at least 80% identical to an amino acid sequence of SEQ ID NO:4,
d) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-8, and
e) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-8.

2 more elements

Dependencies are inferred from the claim text.