Sustained release compositions
OwnerYoshio Hata, Yutaka Yamagata +1inventors
InventorsYoshio Hata, Yutaka Yamagata, Yasutaka Igari
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Abstract
A composition prepared by containing or blending a physiologically active non-peptide substance and a biodegradable polymer having two or more carboxylic groups at its end or a salt thereof features: (1) larger content of the physiologically active non-peptide substance can be contained, as well as release of the same can be controlled or accelerated, whereby secure pharmaceutical effect is achieved; (2) when the physiologically active non-peptide substance causes subcutaneous stimulation, an activity of canceling the stimulation by strongly acidic group at its end is expected; and (3) high glass transition point and high stability.
Claims21
A composition comprising a physiologically active non-peptide substance and a biodegradable polymer having two or more carboxylic groups at its end or a salt thereof.
A composition in which a physiologically active non-peptide substance and a biodegradable polymer having two or more carboxylic groups at its end or a salt thereof are blended.
A method for producing a composition characterized by blending a physiologically active non-peptide substance with a biodegradable polymer having two or more carboxylic groups at its end, or a salt thereof.
Dependencies are inferred from the claim text.