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US 2004/0023929 A1Published application
Small molecules for inhibition of function and drug delivery to leukocytes
AssigneesScience & Technology Corporation @ UNM, Regents of the University of Minnesota
InventorsRichard S. Larson, Carston R. Wagner
Life of this patent
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Abstract
The present invention provides a compound and a method of making a compound according to the following formula: 1 where R1 is an alkyl group having 1 to 12 carbons; R2 is a urea group; R3 is an active group, such as fluorescein, a toxin, radiolabel or drug; and R4, R5 and R6 are each independently a halide group.
Claims29
A molecule comprising the following formula:
- 26
- wherein R1 is an alkyl group or an aryl group;
- R2 is a urea group, phosphate group, phosphoramidate group or a sulfonate group;
- R3 is an active group;
- and
- R4, R5 and R6 are each independently a halide group.
3 more elements
A molecule comprising the following formula:
- 27
A method for forming a molecule comprising the steps of:
- (a) providing a compound (1) having the following formula:
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- and
- (b) reacting compound (1) with fluorescein N-isothiocyanate to thereby form a compound (2) having the following formula:
- 29
2 more elements
Dependencies are inferred from the claim text.