Antisense modulation of a20 expression
OwnerC Frank Bennett, Jacqueline R Wyattinventors
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of A20. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding A20. Methods of using these compounds for modulation of A20 expression and for treatment of diseases associated with expression of A20 are provided.
Claims20
A compound 8 to 50 nucleobases in length targeted to a nucleic acid molecule encoding A20, wherein said compound specifically hybridizes with and inhibits the expression of A20.
A compound 8 to 50 nucleobases in length which specifically hybridizes with at least an 8-nucleobase portion of an active site on a nucleic acid molecule encoding A20.
Dependencies are inferred from the claim text.