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US 2004/0023862 A1Published application
Uses of bombesin receptor 3
AssigneeSmithKline Beedham p. l. c.
InventorsDarren Smart, Paul J L M Strijbos
Life of this patent
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Abstract
The invention relates to newly identified uses of BRS3 polypeptides and polynucleotides encoding such polypeptides, to their use in therapy of ischemia, of neurodegenerative diseases, of memory and attention disorders, and in identifying compounds which may be agonists, antagonists and/or inhibitors which are potentially useful in therapy, and to production of such polypeptides and polynucleotides.
Claims12
The use of a compound selected from:
- (a) a BRS3 polypeptide;
- (b) a compound which activates a BRS3 polypeptide;
- (c) a compound which inhibits a BRS3 polypeptide;
- or
- (d) a polynucleotide encoding a BRS3 polypeptide, for the manufacture of a medicament for treating:
- (i) stroke;
- (ii) ischaemia;
- (iii) head injury;
- (iv) Alzheimer's disease;
- (v) Parkinson's disease;
- (vi) learning;
- or
- (vii) memory and attention disorders.
10 more elements
The use of [D-Phe6, βAla11, Phe13, Nle14]Bombesin(6-14) or [D-Tyr6, βAla11, Phe13, Nle14]Bombesin(6-14) for the manufacture of a medicament for treating:
- (i) stroke;
- (ii) ischaemia;
- (iii) head injury;
- (iv) Alzheimer's disease;
- (v) Parkinson's disease;
- (vi) learning;
- or
- (vii) memory and attention disorders.
5 more elements
Dependencies are inferred from the claim text.