Carrageenan viscoelastics for ocular surgery
AssigneeAlcon Inc.
InventorsMutlu Karakelle, Michael R Brunstedt
Life of this patent
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Abstract
Disclosed are carrageenan-based transitional viscoelastics that will induce little or no IOP spike when left in the eye at the close of surgery thereon. Drug delivery systems for delivering therapeutic agents during post-operative recovery stages are also disclosed.
Claims12
A transitional viscoelastic composition for use in surgery, comprising a sterile, non-inflammatory, aqueous solution comprising kappa-carrageenan, potassium, and a second sulfated polysaccharide, such solution having a viscosity transition temperature range, wherein such solution exhibits a loss of viscosity of at least 80% upon heating through such viscosity transition temperature range.
A transitional viscoelastic composition for delivering an ophthalmic drug to an affected eye, comprising a sterile, aqueous solution comprising kappa-carrageenan, potassium, and a second sulfated polysaccharide, such solution having a viscosity transition temperature range, wherein such solution exhibits a loss of viscosity of at least 80% upon warming through such viscosity transition temperature range.
A method of protecting, manipulating or stabilizing tissue in an eye during surgery thereon, comprising instilling in the eye the transitional viscoelastic composition of any of the foregoing claims.
Dependencies are inferred from the claim text.