Glutathione derivatives and their dosage forms
AssigneeTeijin Limited
InventorsKiyoyuki Sakon, Yoshimitsu Naniwa, Mitsuru Kobayashi, Daishiro Miura, Hiroshi Imai, Atsushi Imaizumi
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AssigneeTeijin Limited
InventorsKiyoyuki Sakon, Yoshimitsu Naniwa, Mitsuru Kobayashi, Daishiro Miura, Hiroshi Imai, Atsushi Imaizumi
Estimating the term…
A glutathione derivative having a dramatically enhanced hematopoiesis promoting effect in the living body, said derivative being represented by the formula (I): 1 wherein, A represents H or a C1-C20 acyl group, R1 represents a C1-C26 alkyl group or a C3-C26 alkenyl group, and R2 represents H, a C1-C26 alkyl group, or a C3-C26 alkenyl group, provided that cases in which R1 represents a C1-C10 alkyl group or a C3-C10 alkenyl group and R2 represents H, a C1-C10 alkyl group, or a C3-C10 alkenyl group are excluded, a salt of said glutathione derivative, or a colloidal composition that enables the safe and effective development of the effects of said glutathione derivative in the living body.
A glutathione derivative represented by the formula (I):
A pharmaceutical composition having an enhanced retention in the blood comprising a substance that has a carboxyl group and an ability of inhibiting or binding glutathione S-transferase wherein the carboxyl group has been changed to a C12-C26 alkyl or alkenyl ester.
Dependencies are inferred from the claim text.