US 2004/0006046 A1 · Malto-oligosaccharide derivatives and use thereof

Abstract

The present invention provides a substance which strongly inhibits human α-amylase and is effective for the prevention and treatment of hyperglycemia, for example, diabetes and the diseases caused thereby, and an α-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia containing the said substance as active principle. Maltoligosaccharide derivatives represented by the following formula: 1 (wherein n is an integer of 0 to 2; m is an integer of 0 to 2; and X represents a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts are provided, and they are contained as active principle to prepare an α-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia such as diabetes.

Claims10

Dependent claims

Maltoligosaccharide derivatives represented by the formula:

10
(wherein n is an integer of 0 to 2;
m is an integer of o to 2;
and X represents a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

10/297,408Filed 6 Dec 2002

Priority

JP 2000-1683636 Jun 2000

Published

8 Jan 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification8 codes

C07H 5/02
Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen,…:…
A61K 31/706
Having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides: containing six-membered rings with nitrogen as a ring hetero atom
A61P 3/10
For glucose homeostasis: for hyperglycaemia, e.g. antidiabetics
A61P 43/00
Drugs for specific purposes, not provided for in groups a61p1/00-a61p41/00

Malto-oligosaccharide derivatives and use thereof

Life of this patent

Malto-oligosaccharide derivatives and use thereof

Life of this patent

Abstract

Claims10