Method of fixing biopolymers to a substrate using magnetic beads and biopolymer measuring equipment using the method
AssigneeYokogawa Electric Corporation
InventorKazuhisa Fukushima
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Abstract
According to the present invention, biopolymers are fixed to a substrate by attaching probe DNA to magnetic beads and fixing the above magnetic beads to the substrate by attracting them using a magnetic attraction. As described above, since magnetic beads with probe DNA attached are fixed to the substrate by attracting them using a magnetic force, the above-mentioned magnetic beads can be fixed with a force stronger than the conventional bonding of probe DNA with the substrate. Accordingly, the magnetic beads are not in danger of exfoliation from the substrate or washing-away of probe DNA during washing treatment.
Claims7
A method for fixing biopolymers to a substrate using magnetic beads, in which the magnetic beads with biopolymer fragments attached are arranged on the surface of a substrate and then said magnetic beads are attracted and fixed to the surface of said substrate by making a magnetic attraction act upon said magnetic beads from the opposite side surface of said substrate.
Biopolymer measuring equipment for detecting the presence of a specific target biopolymer fragment using hybridization;
- comprising
- a vessel, composed of a substrate and a cover mounted closely sticking to the substrate, in which magnetic beads with biopolymer fragments attached are arranged on said substrate and a solution containing target biopolymers is poured, and
- a magnetic attraction generating means positioned in the opposite side of said substrate;
- and being configured so that said magnetic beads are fixed to the surface of said substrate by being attracted by the magnetic attraction of said magnetic attraction generating means.
Dependencies are inferred from the claim text.