Novel polypeptide-human an1-like protein 16 and the polynucleotide encoding the same
OwnerYumin Mao, Yi Xieinventors
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Abstract
A new polypeptide-human AN1-like protein 16, the polynucleotide encoding the same, as well as a method of producing said polypeptide by DNA recombinant techniques. The present invention also discloses methods of using the polypeptide in the treatment of various diseases, such as malignant tumors, blood diseases, HIV infections, immunological diseases, a wide variety of inflammations and developmental disorders. The invention also discloses agonists and antagonists of the polypeptide and the therapeutic uses thereof. Also disclosed is the uses of polynucleotides coding for the new human AN1-like protein 16.
Claims18
An isolated polypeptide-human AN1-like protein 16-comprising a polypeptide having the amino acid sequence of SEQ ID NO:
- 2, its active fragments, analogues and derivatives.
4 An isolated polynucleotide selected from the group consisting of:
- (a) the polynucleotide encoding a polypeptide having an amino acid sequence of SEQ ID NO:
- 2 or its fragment, analogue, derivative;
- (b) the polynucleotide complementary to polynucleotide (a);
- and
- (c) the polynucleotide sharing at least 70% identity to polynucleotide (a) or (b).
The polynucleotide of claim 4 comprising a polynucleotide encoding an amino acid sequence of SEQ ID NO:
- 2.
The polynucleotide of claim 4 wherein the sequence of said polynucleotide comprises position 300-737 of SEQ ID NO:
- 1 or position 1-895 of SEQ ID NO:
- 1.
An antibody specifically which binds bound specifically with human AN1-like protein 16.
A compound simulating or regulating the activity or expression of the polypeptide which is the compound simulating, improving, antagonizing, or inhibiting the activity of human AN1-like protein 16.
Dependencies are inferred from the claim text.