Methods for treating crohn's and other TNF associated diseases
OwnerEric Altschulerinventor
Life of this patent
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Abstract
A new method employing a known compound, bupropion hydrochloride (±)-1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride, and its analogues, in a new use for the treatment of TNF-related disorders is described.
Claims9
A method for treating Crohn's Disease in patients without causing beta-andrenergic receptor down-regulation, comprising
- administering bupropion in an effective dose to alleviate or eliminate symptoms and gut pathology, and
- monitoring the patient's CDAI level wherein the dose is adjusted according to degree of alleviation and elimination of symptoms
A method for treating TNF associated diseases without causing beta-andrenergic receptor down-regulation, comprising
- administering bupropion in an effective dose to alleviate or eliminate TNF associated disease symptoms and pathology;
- and
- monitoring the patient's response wherein the dose is adjusted according to degree of alleviation and elimination of the symptoms and pathology
A method for treating rheumatoid arthritis in patients without causing beta-andrenergic receptor down-regulation, comprising.
- administering bupropion in an effective dose to alleviate or eliminate symptoms and pathology;
- and
- monitoring the patient's response wherein the dose is adjusted according to degree of alleviation and elimination of symptoms.
A method for treating psoriasis in patients without causing beta-andrenergic receptor down-regulation, comprising.
- administering bupropion in an effective dose to alleviate or eliminate symptoms and pathology, and
- monitoring the patient's response wherein the dose is adjusted according to degree of alleviation and elimination of symptoms
A method for treating IgA nephropathy in patients without causing beta-andrenergic receptor down-regulation, comprising.
- administering bupropion in an effective dose to alleviate or eliminate symptoms and pathology, and
- monitoring the patient's response wherein the dose is adjusted according to degree of alleviation and elimination of symptoms
A method for treating anemia in patients without causing beta-andrenergic receptor down-regulation, comprising:
- administering bupropion in an effective dose to alleviate or eliminate symptoms and pathology, and
- monitoring the patient's response wherein the dose is adjusted according to degree of alleviation and elimination of symptoms
A method for treating myelodysplasia in patients without causing beta-andrenergic receptor down-regulation, comprising.
- administering bupropion in an effective dose to alleviate or eliminate symptoms and pathology;
- and
- monitoring the patient's response wherein the dose is adjusted according to degree of alleviation and elimination of symptoms
Dependencies are inferred from the claim text.