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US 2004/0002543 A1Published application
Compositions comprising GABA analogs and a decongestant to relieve sinus headache pain
OwnerLeslie Magnus, Catherine Segalinventors
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Abstract
This invention is composition and method for treating sinus headache or sinus pains including analogs of glutamic acid and gamma-aminobutyric acid in combination with a decongestant.
Claims20
A method for treating sinus headache or sinus pain, comprising administering a pharmaceutical composition comprising:
- (a) an analgesically effective amount of a GABA analog;
- and
- (b) an effective amount of a decongestant.
12 A composition for eliciting an enhanced analgesic response in a mammal comprising:
- (a) an analgesically effective amount of a GABA analog;
- and
- (b) an effective amount of a decongestant.
The composition according to claim 12, wherein the GABA analog the compound according to Formula I:
- 5
- wherein R1 is hydrogen or lower alkyl and n is an integer of from 4 to 6, and the pharmaceutically acceptable salts thereof.
The composition according to claim 12, wherein the GABA analog is a compound according to Formula II:
- 6
- wherein R2 is a straight or branched alkyl of from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms;
- R3 is hydrogen or methyl;
- and R4 is hydrogen, methyl, or carboxyl.
1 more element
Dependencies are inferred from the claim text.