Phospholipase D inhibitors and uses thereof
AssigneeCell Therapeutics, Inc.
InventorsJ. Peter Klein, Anil M. Kumar, Marc J. McKennon
Life of this patent
Estimating the term…
Abstract
The invention is directed to thiazolidinones and the use thereof to inhibit phospholipase D (PLD) activity. The invention further relates to methods of treating cancer and inflammatory diseases using thiazolidinones.
Claims46
A method for inhibiting phospholipase D (PLD), comprising contacting PLD with an amount of a thiazolidinone or a pharmaceutically acceptable salt, composition and prodrug thereof, effective in inhibiting PLD.
A method for treating cancer, comprising administering to a subject in need thereof an effective amount of a thiazolidinone, or a pharmaceutically acceptable salt, composition and prodrug thereof.
A method for treating inflammation, comprising administering to an animal in need thereof an effective amount of a thiazolidinone, or a pharmaceutically acceptable salt, composition and prodrug thereof.
Dependencies are inferred from the claim text.