Vaccination or immunization using a prime-boost regimen
OwnerJean-Christophe Francis Audonnet, Laurent Bernard Fischer +1inventors
InventorsJean-Christophe Francis Audonnet, Laurent Bernard Fischer, Simona Barzu-Le-Roux
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Abstract
Disclosed and claimed are methods and compositions and kits for the vaccination or immunization of an animal, such as a mammal, advantageously a bovine, involving a prime-boost regimen.
Claims32
A prime-boost vaccination method against a bovine pathogen, comprising administering to a bovine a first, priming vaccine or immunogenic or immunological composition against the bovine pathogen, wherein the first, priming vaccine or immunogenic or immunological composition comprises a DNA vaccine or immunological or immunogenic composition comprising nucleic acid molecule(s) encoding and expressing in vivo in the bovine at least one immunogen from the bovine pathogen, and thereafter administering a second, boosting vaccine or immunological or immunogenic composition against the bovine pathogen that is different than the first, priming vaccine or immunological or immunogenic composition, but contains or expresses at least one immunogen of the bovine pathogen which is the same immunogen of the bovine pathogen expressed by the first, priming vaccine or immunological or immunogenic composition.
The kit of claim 32, wherein (a) and (b) are in separate containers in the same package.
Dependencies are inferred from the claim text.