Polyphosphate-water soluble collagen complexes and process for preparation thereof
AssigneesToshikazu SHIBA, Shibarie Research Institute
InventorsToshikazu Shiba, Toshie Shiba, Minoru Yamaoka, Takashi Uematsu, Yoshiharu Takahashi, Hitoshi Tanaka
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Abstract
A polyphosphate-collagen complex, comprising at least one polyphosphate bound to collagen, a process for preparing the complex, and a method for promoting tissue regeneration using the complex.
Claims19
A polyphosphate-collagen complex, comprising at least one polyphosphate bound to collagen.
A process for preparing a polyphosphate-collagen complex, which comprises mixing a polyphosphate solution at a concentration of 0.5 to 10% by weight with a collagen solution at a concentration of 0.1 to 10% by weight, and collecting the generated precipitate.
A method for concentrating and separating polyphosphates having an average chain length of 60 to 70, which comprises mixing, at a volume ratio of between 2:1 and 9:1, a hexametaphosphate solution at a concentration of 0.1 to 10% by weight with 87 to 100% ethanol, and separating the precipitated polyphosphates from a reaction solution.
Dependencies are inferred from the claim text.