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US 2004/0002161 A1Published application
Analytical test cartridge; and, methods
AssigneeDiametrics Medical, Inc.
InventorKee Van Sin
Life of this patent
Estimating the term…
Abstract
An analytical test cartridge is provided. The analytical test cartridge can be used for medical analyses of liquid samples removed from a patient, for example blood. The analytical test cartridge is configured to provide for titration experiments. An example of a titration experiment that can be performed with the arrangement, is titration of heparin with protamine. Methods of assembly and use are provided.
Claims21
A sample analysis cartridge comprising:
- (a) a liquid sample inlet;
- (b) a main flow channel in fluid flow communication with the inlet;
- (c) a titration cell arrangement including:
- at least two titration spurs in fluid flow communication with the main flow channel;
- and, a titration cell in each spur;
- (d) a titration sensor arrangement including a sensor positioned in each titration cell in the titration cell arrangement;
- and
- (e) a titration agent positioned in each titration cell of the titration cell arrangement, with a different amount of titration agent in at least two of the titration cells.
5 more elements
A method of defining an analyte presence in a liquid sample;
- said method including steps of:
- (a) directing a liquid sample into a plurality of spurs in fluid flow communication with a single main flow channel;
- (b) titrating at least one of a selected analyte and a selected reagent in the liquid sample to a different degree in selected ones of the plurality of the spurs;
- and,
- (c) calculating an amount of a analyte in the liquid sample based on a titration analysis determined by the step of titrating.
2 more elements
Dependencies are inferred from the claim text.