US 2004/0002122 A1 · Human neuronal nicotinic acetylcholine receptor compositions and methods employing same

Abstract

DNA encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing said DNA, methods for producing alpha and beta subunits and recombinant (i.e., isolated or substantially pure) alpha subunits (specifically α6) and beta subunits (specifically β3) are provided. In addition, combinations of a plurality of subunits (i.e., one or more of α1, α2, α3, α4, α5, α6 and/or α7 subunits in combination with one or more of β3 subunits are provided.

Claims34

Dependent claims

Isolated DNA comprising a sequence of nucleotides encoding an α6 subunit of a human neuronal nicotinic acetylcholine receptor.

Dependencies are inferred from the claim text.

Facts

Application

10/303,198Filed 25 Nov 2002

Priority

7 Jun 1995

Published

1 Jan 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification5 codes

G01N 33/5008
Involving human or animal cells: for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
C07K 14/70571
Receptors; Cell surface antigens; Cell surface determinants: for neuromediators, e.g. serotonin receptor, dopamine receptor
G01N 33/566
Immunoassay; Biospecific binding assay; Materials therefor: using specific carrier or receptor proteins as ligand binding reagents where possible…
G01N
Investigating or analysing materials by determining their chemical or physical properties

Abstract

Claims34

Dependent claims

Isolated DNA comprising a sequence of nucleotides encoding an α6 subunit of a human neuronal nicotinic acetylcholine receptor.

Dependencies are inferred from the claim text.

Human neuronal nicotinic acetylcholine receptor compositions and methods employing same

Life of this patent

Abstract

Claims34

Human neuronal nicotinic acetylcholine receptor compositions and methods employing same

Life of this patent

Abstract

Claims34