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AssigneeShiseido Company, Ltd.
InventorsSatoshi Amano, Yuki Ogura, Yukiko Matsunaga, Takanari Tsuda, Yukari Aoyama, Nobuyoshi Koga
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The invention provides an epidermal basement membrane structure formation accelerating preparation and a skin external preparation comprising a serine protease inhibitor, and optionally an accelerator of production of extracellular matrix protein components of the epidermal basement membrane. It also provides, as a means for producing artificial skin having an adequately formed basement membrane, an artificial skin-forming medium which comprises a serine protease inhibitor, and optionally an accelerator of production of extracellular matrix protein components of the epidermal basement membrane and a matrix metalloprotease inhibitor, as well as a method for producing the same.
A skin basement membrane structure formation accelerating preparation comprising one or more serine protease inhibitors as active ingredients.
A method for producing an artificial skin, comprising a step of culturing an artificial skin-forming medium, characterized by adding one or more serine protease inhibitors to said artificial skin-forming medium.
A skin external preparation characterized by comprising extract from a plant belonging to Fagaceae Fagus, a 1-acyl lysophospholipid represented by the following general formula (1) or (2), and an extract from a plant belonging to Labiatae Mentha.
Dependencies are inferred from the claim text.