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US 2004/0001879 A1Published application
Hemostatic wound dressing and method of making same
AssigneeEthicon, Inc.
InventorsJian Xin Guo, Dwayne Lee Looney, Guanghui Zhang, Anne Jessica Gorman
Life of this patent
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Abstract
The present invention is directed to wound dressings that contain a fabric made from biocompatible polymeric fibers and having flexibility, strength and porosity effective for use as a hemostat, and a porous, polymeric matrix prepared from a biocompatible, water-soluble or water-swellable polymer dispersed through the fabric; and to methods of making such wound dressings.
Claims25
A hemostatic wound dressing, comprising:
- a fabric, said fabric comprising a wound-contacting surface and a top surface opposing said wound-contacting surface, said fabric comprising fibers and having flexibility, strength and porosity effective for use as a hemostat, said fibers comprising a biocompatible polymer;
- and
- a porous, polymeric matrix applied to said wound-contacting surface and dispersed at least partially through said fabric, said porous polymeric matrix comprising a biocompatible, water-soluble or water-swellable polymer.
A hemostatic fabric, comprising knitted fibers, said fibers comprising a biocompatible polymer;
- and
- a porous, biocompatible, water-soluble or water-swellable polymeric matrix dispersed at least partially through said fabric in amounts effective to provide hemostasis.
A process for making a wound dressing:
- comprising,
- providing a solution having substantially dissolved therein a water-soluble or water-swellable biocompatible polymer,
- providing a fabric having a top surface and a bottom surface opposing said top surface, said fabric comprising fibers and having flexibility, strength and porosity effective for use as a hemostat, said fibers comprising a biocompatible polymer,
- contacting said solution with said fabric under conditions effective to distribute said solution through said fabric,
- lyophilizing said fabric having said solution distributed there through, thereby providing a porous polymeric matrix comprising said water-soluble or water-swellable polymer dispersed through said fabric.
2 more elements
Dependencies are inferred from the claim text.