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US 2003/0232884 A1Published application
New pharmaceutical formulation
AssigneeCritical Therapeutics, Inc.
InventorMitchell P. Fink
Life of this patent
Estimating the term…
Abstract
Disclosed is a pharmaceutical composition comprising an ester of an alpha-ketoalkanoic acid or an amide of an alpha-ketoalkanoic and lactic acid or a pharmaceutically acceptable salt of lactic acid dissolved in aqueous solution.
Claims19
A pharmaceutical composition comprising:
- (a) an ester of an alpha-ketoalkanoic acid or an amide of an alpha-ketoalkanoic;
- and
- (b) lactic acid or a pharmaceutically acceptable salt of lactic acid dissolved in aqueous solution.
A pharmaceutical composition comprising:
- (a) an ester of an alpha-ketoalkanoic acid;
- and
- (b) lactic acid or a pharmaceutically acceptable salt of lactic acid, dissolved in aqueous solution.
An aqueous pharmaceutical composition comprising:
- (a) from 0.1% to 1.0% by weight of ethyl pyruvate;
- and
- (b) sodium or potassium lactate at a concentration from about 1 mM to about 100 mM.
A pharmaceutical composition comprising:
- (a) about 2% to about 5% by weight of ethyl pyruvate;
- (b) about 50 to about 150 mM of NaCl;
- (f) about 1 to about 8 mM of KCl;
- (g) about 1 to about 5 mM of CaCl2;
- and
- (h) about 10 to about 40 mM of sodium lactate,
- wherein the ingredients (a) through (e) are dissolved in an aqueous solution.
4 more elements
A pharmaceutical composition comprising from about 0.1% to about 10% by weight of ethyl pyruvate in Ringer's Lactate solution.
Dependencies are inferred from the claim text.