Method and apparatus for treatment of tissue adjacent a bodily conduit with a compression balloon

An apparatus for treatment of tissue within a body requiring thermotherapy, said apparatus comprising:

• a) a catheter to be inserted into a bodily conduit;
• b) an energy-emitting source disposed within said catheter;
• c) a compression balloon surrounding the energy-emitting source within said catheter, said compression balloon having an inflated diameter that is greater than that of the bodily conduit in a relaxed state and having an outside surface of the balloon coated with at least one of a gene modifier and a drug or medication;
• d) anchoring means for positioning said energy-emitting source and said compression balloon adjacent the tissue to be treated;
• e) means for activating the energy-emitting source to radiate energy to heat the coated, compression balloon and tissue to be treated wherein the heat of the energized energy-emitting source one of releases, activates and enhances the at least one of the gene modifier, and the drug or medication coated on the compression balloon;
• and
• f) means for terminating the radiation of energy from the energy-emitting source upon completion of the time period to destroy diseased tissue whereby the heated, coated compression balloon effectively delivers the at least one of the gene modifier, and the drug or medication to a target area of the diseased tissue.

A method of thermotherapy for treating tissue adjacent a bodily conduit comprising the steps of:

• inserting an energy-emitting source containing catheter into a bodily conduit so that an energy-emitting source is positioned in a region of the prostate in order to radiate energy that heats tissue to be treated adjacent the bodily conduit;
• inflating a compression balloon on the catheter that surrounds the energy-emitting source with a fluid and upon inflating the compression balloon to the desired dimension, stopping circulation of the fluid;
• energizing the energy-emitting source to a low power where the amount of power depends upon the bodily conduit being treated;
• heating a portion of the tissue surrounding the bodily conduit to a sufficiently high temperature, depending upon the coated, compression balloon and the treatment to be performed, for a time sufficient to destroy a heated portion of the tissue via the energy-emitting source;
• and
• terminating the heating of the tissue upon completion of the time sufficient to destroy the heated portion of the tissue.

A method of thermotherapy for treating tissue adjacent a bodily conduit comprising the steps of:

• injecting at least one of a gene modifier, and drug or medication into an area adjacent the tissue to be treated;
• inserting an energy-emitting source containing catheter into a bodily conduit so that an energy-emitting source is positioned in a region of the prostate in order to radiate energy that heats tissue to be treated adjacent the bodily conduit;
• inflating a compression balloon on the catheter that surrounds the energy-emitting source with a fluid;
• alternating compression and decompression of the compression balloon against the bodily conduit to be treated so that the bodily conduit and surrounding tissue is mechanically manipulated causing at least one of the intravenously injected gene modifier, and the drug or medication to be effectively delivered to a target area of the tissue to be treated;
• energizing the energy-emitting source to a low power in the range of 0 watts to approximately 20 watts;
• heating a portion of the tissue surrounding the bodily conduit to a temperature of approximately 43° C. for a time sufficient to destroy a heated portion of the tissue via the energy-emitting source;
• and
• terminating the heating of the tissue upon completion of the time sufficient to destroy the heated portion of the tissue wherein the inflated compression balloon reduces blood flow in the tissue being treated and tissue adjacent the bodily conduit is maintained at a temperature above 30° C. to produce a biological stent.