Anti-inflammatory agents
OwnerWerner Baschong, Helmut Luther +2inventors
InventorsWerner Baschong, Helmut Luther, Dietmar Ochs, Sebastien Mongiat
Life of this patent
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Abstract
Disclosed is the use of hydroxydiphenylether compounds of formula 1 R1, R2 and R3, independently from each other are hydrogen; hydroxy; C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; C1-C20alkoxy; C1-C6alkylcarbonyl; phenyl; or phenyl-C1-C3alkyl; R4 is hydrogen, C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; hydroxy; formyl; acetonyl; allyl; carboxy; carboxy-C1-C3alkyl; carboxyallyl; C2-C20alkenyl; C1-C6-alkyl-carbonyl; C1-C3alkylcarbonyl-C1-C3alkyl; phenyl; or phenyl-C1-C3alkyl; and R5 is hydrogen; C1-C20alkoxy; or C1-C6alkylcarbonyl; as pharmaceutical active agents and to pharmaceutical compositions containing them.
Claims15
75
- R1, R2 and R3, independently from each other are hydrogen;
- hydroxy;
- C1-C20alkyl;
- hydroxy-substituted C1-C20 alkyl;
- C5-C7cycloalkyl;
- C1-C20alkoxy;
- C1-C6alkylcarbonyl;
- phenyl;
- or phenyl-C1-C3alkyl;
- R4 is hydrogen, C1-C20alkyl;
- hydroxy-substituted C1-C20alkyl;
- C5-C7cycloalkyl;
- hydroxy;
- formyl;
- acetonyl;
- allyl;
- carboxy;
- carboxy-C1-C3alkyl;
- carboxyallyl;
- C2-C20alkenyl;
- C1-C6-alkyl-carbonyl;
- C1-C3alkylcarbonyl-C1-C3alkyl;
- phenyl;
- or phenyl-C1-C3alkyl;
- and
- R5 is hydrogen;
- C1-C20alkoxy;
- or C1-C6alkylcarbonyl;
- for use as a therapeutic agent.
Dependencies are inferred from the claim text.