Novel diphosphine compound, production intermediate thereof, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex
AssigneeTakasago International Corporation
InventorsTohru Yokozawa, Takao Saito
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Abstract
The present invention provides a novel phosphine compound, specifically to provide a novel phosphine compound useful as a ligand for the above catalysts, in particular, a novel catalyst having an excellent performance (chemical selectivity, enantio-selectivity, catalytic activity) as a catalyst for asymmetric synthetic reactions, particularly asymmetric hydrogenation. A diphosphine compound represented by the general formula (1): 1 wherein R1 and R2 each independently represents a lower alkyl group, a cycloalkyl group, an unsubstituted or substituted phenyl group, or a five-membered heteroaromatic ring residue.
Claims7
A diphosphine compound represented by the general formula (1):
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- wherein R1 and R2 each independently represents a lower alkyl group, a cycloalkyl group, an unsubstituted or substituted phenyl group, or a five-membered heteroaromatic ring residue.
A compound represented by the general formula (2):
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- wherein n is an integer of 1 to 3.
A compound represented by the general formula (3):
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- wherein R3 and R4 each independently represents a hydroxy group, a protected hydroxy group, a lower alkoxy group, a chlorine atom, or a bromine atom.
Dependencies are inferred from the claim text.