Back to results
US 2003/0228682 A1Published application
Fluorescence sensing
AssigneeUniversity of Maryland, Baltimore
InventorsJoseph R. Lakowicz, Chris D. Geddes
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeUniversity of Maryland, Baltimore
InventorsJoseph R. Lakowicz, Chris D. Geddes
Estimating the term…
An apparatus and a method for detecting or measuring the presence of a compound capable of fluorescing in a sample. The Apparatus may contain a metal particle and a compound capable of fluorescing separated by at least one film spacer layer. The thickness of the film enhances the fluorescence of said compound due to the distance of the compound from the metal particle. The method includes spacing the compound at a distance from a metal particle, which provides an enhanced fluorescence intensity of the compound, exposing the compound to radiation and detecting the fluorescent emission. The Apparatus may also be in the form of multiple metal particles in a porous three dimensional matrix. The method also includes flowing the compound through a porous three dimensional matrix comprising multiple metal particles.
An apparatus for detecting or measuring the presence of a compound capable of fluorescing in a sample comprising a metal in the form of a particle or a film, at least one film spacer layer, said compound capable of fluorescing, and a source of irradiation, wherein the metal particle or metal film and the compound are separated by said at least one film spacer layer.
An apparatus for detecting or measuring the presence of a compound capable of fluorescing in a sample, comprising metal particles, said compound capable of fluorescing, a porous substrate in the form of a three dimensional matrix and a source of irradiation, wherein the metal particles are on the surface of the porous substrate or the metal particles are embedded in the porous substrate.
An apparatus for detecting or measuring the presence of a compound capable of fluorescing in a sample comprising metal particles, said compound capable of fluorescing, and a source of irradiation, wherein the metal particles form a porous three dimensional matrix.
A method for detecting the presence of a compound comprising:
A method for detecting the presence of a compound comprising:
Dependencies are inferred from the claim text.