US 2003/0228587 A1 · Nucleic acid molecule encoding IWU-1

Abstract

The present invention relates to an isolated nucleic acid molecule encoding an IWU-1 protein or polypeptide; an isolated IWU-1 protein or polypeptide encoded by the nucleic acid molecule of the present invention; an isolated antibody against the protein or polypeptide encoded by the nucleic acid molecule; and uses for the nucleic acid molecule, the protein, and its antibody, including in the making of a vaccine, and in various in methods, including for detection of IWU-1 in a biological sample; treating a disease condition in a subject; regulating IWU-1 expression in a subject, and in methods of screening drugs that regulate IWU-1 expression. Also disclosed are vectors, host cells, and transgenic animals having the nucleic acid molecule encoding an IWU-1 protein or polypeptide of the present invention.

Claims76

Dependent claims

An isolated nucleic acid molecule encoding an IWU-1 protein or polypeptide, wherein the nucleic acid molecule either:

1) has a nucleotide sequence of SEQ ID NO:
1;
2) encodes a protein or polypeptide having an amino acid sequence of SEQ ID NO:
2;
3) has a nucleotide sequence that is at least 55% similar to the nucleotide sequence of SEQ ID NO:
1 by basic BLAST using default parameters analysis, or 4) hybridizes to the nucleotide sequence of SEQ ID NO:
1 under stringent conditions characterized by a hybridization buffer comprising 5×SSC at a temperature of 55° C.

4 more elements

Dependencies are inferred from the claim text.

Nucleic acid molecule encoding IWU-1

Life of this patent

Nucleic acid molecule encoding IWU-1

Life of this patent

Abstract

Claims76