Volume maintaining osteoinductive/osteoconductive compositions
OwnerNelson L. Scarborough, Sergio Gadaleta +2inventors
InventorsNelson L. Scarborough, Sergio Gadaleta, David Kaes, Albert Manrique
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Abstract
An osteoinductive/osteoconductive composition prepared from a quantity, of demineralized fibrous bone elements possessing an average surface area to volume ratio of about 100:1 to about 20:1, a quantity of mostly shaped regular non-fibrous bone elements possessing an average surface area to volume ratio of about 10:1 or less and a sufficient quantity of biocompatible fluid carrier sufficient to provide the composition as a deformable mass is provided herein. Also provided is a method of using the composition to repair a bone defect site.
Claims24
An osteoinductive/osteoconductive composition comprising:
- (a) a quantity of demineralized fibrous bone elements possessing an average surface area to volume ratio of about 100:1 to about 20:1, (b) a quantity of shaped non-fibrous bone elements possessing an average surface area to volume ratio of about 10:1 or less and, (c) a sufficient quantity of biocompatible fluid carrier sufficient to provide the composition as a deformable mass.
Dependencies are inferred from the claim text.