Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
AssigneeCuris, Inc.
InventorsThangavel Kuberasampath, Charles M. Cohen, Herrmann Oppermann, Engin Ozkaynak, David C. Rueger, John E. Smart, Roy H.L. Pang
Life of this patent
Estimating the term…
Abstract
The invention is a treatment for increasing the bone mass or preventing bone loss in an individual afflicted with a bone disease which includes administering to the individual a morphogen in a therapeutically effective amount so as to maintain or stimulate bone formation.
Claims41
A therapeutic treatment method for preventing loss of bone mass or increasing bone mass in an individual, the method comprising:
- administering to the individual a therapeutically effective morphogen in an amount and for a time sufficient to prevent loss of or to increase bone mass in said individual.
A therapeutic treatment method for preventing loss of bone mass or for increasing bone mass in an individual, comprising:
- administering an agent that stimulates in vivo the effective concentration of a naturally occurring morphogen in said individual sufficient to prevent loss of or to increase bone mass in said individual.
A method for repairing defects in bone tissue microstructure, comp rising:
- administering to an individual a therapeutically effective morphogen in an amount and for a time sufficient to repair defects in said microstructure.
A method for repairing defects in bone tissue microstructure, comprising:
- administering an agent capable of stimulating in vivo the effective concentration of a naturally occurring morphogen sufficient to repair said defects.
A method for protecting an individual at risk for loss of bone mass, the method comprising:
- providing to the individual a therapeutically effective morphogen in an amount and for a time sufficient to protect said individual from loss of bone mass.
A method for protecting an individual at risk for loss of bone mass, the method comprising:
- providing to the individual an agent that stimulates in vivo a therapeutically effective concentration of a naturally occurring morphogen sufficient to protect said individual from loss of bone mass.
Dependencies are inferred from the claim text.