Alpha-sulfin-and alpha-sulfonamino acid amide derivatives

α-Sulfin- and α-sulfonamino acid amides of formula I

• 190
• including the optical isomers thereof and mixtures of such isomers, wherein
• n is a number zero or one;
• R1 is C1-C12alkyl, C1-C12alkyl substituted with C1-C4alkoxy, C1-C4alkylthio, C1-C4alkylsulfonyl, C3-C8cycloalkyl, cyano, C1-C6alkoxycarbonyl, C3-C6alkenyloxycarbonyl or C3-C6alkynyloxycarbonyl;
• C3-C8cycloalkyl;
• C2-C12alkenyl;
• C2-C12alkynyl;
• C1-C12halogenalkyl;
• or a group NR9R10 wherein R9 and R10 are independently of the other C1-C6alkyl, or together are tetra- or penta-methylene;
• R2 and R3 are each independently hydrogen;
• C1-C8alkyl;
• C1-C8alkyl substituted with hydroxy, mercapto, C1-C4alkoxy or C1-C4alkylthio;
• C3-C8alkenyl;
• C3-C8alkynyl;
• C3-C8cycloalkyl;
• C3-C8cycloalkyl-C1-C4alkyl;
• or the two groups R2 and R3 together with the carbon atom to which they are bonded form a three to eight-membered hydrocarbon ring;
• R4 and R5 are each independently hydrogen or C1-C4alkyl;
• R6 and R7 are independently of each other hydrogen or an organic radical,
• R8 is either hydrogen
• 191
• wherein
• R11, R12, R13, R15 and R17 are each independently hydrogen or C1-C4alkyl,
• R13 is C4-C12alkyl;
• C1-C12halogenalkyl;
• C3-C8cycloalkyl;
• optionally substituted aryl or optionally substituted heteroaryl,
• R16 is optionally substituted aryl or optionally substituted heteroaryl;
• and
• Z is oxygen, sulfur —CR18R19— or —NR20—, wherein R18, R19 and R20 independently of each other are hydrogen or C1-C4alkyl.