Method of designing multifunctional base sequence

Abstract

To provide a method of designing a multifunctional base sequence which can largely shorten the calculation time and reduce the volume of memory consumption of a processor by carrying out calculation with the advance exclusion of base sequences in which translation termination codons are emerged in the second and third reading frames which are to be excluded in the end. Focusing on the fact that a dipeptide sequence already contains information about the translation products of the second and third reading frames, proteins are analyzed and calculated as duplicated connective products of dipeptide sequences, and not analyzed as connective products of 20 kinds of amino acids. In “Leu-Ser” case, for example, calculation may only be performed hereafter for 6×6−10=26 variants that do not contain termination codons in the second and third reading frames (FIG. 1). Further, in the case of “Leu-Ser-Arg” sequence, by selecting the combinations having the same codon for serine from 26 variants of “Leu-Ser” 6-mer codons and from 32 variants of “Ser-Arg” 6-mer codons, and connecting them, from now on, calculation would be performed only for 142 variants out of 218 variants, and connected.

Dependencies are inferred from the claim text.