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US 2003/0215932 A1Published application
Process for the isolation of lovastatin
AssigneeRanbaxy Laboratories Limited
InventorsParveen Kumar, S. Rama, Pardeeo Narula
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Abstract
The process for the preparation and isolation of the hypolipaemic active substance lovastatin in substantially pure form having a purity of at least 95% which comprises lactonizing the mevinolinic acid to lovastatin in a totally aqueous medium.
Claims15
A process for effecting the lactonization of mevinolinic acid of Formula II
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- in an aqueous medium and isolating the corresponding lovastatin of Formula I
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- in substantially pure form from the solution thereof.
1 more element
Dependencies are inferred from the claim text.