Streptavidin proteins
AssigneeThe Regents of the University of California
InventorsTakeshi Sano, Alexander N. Glazer, Charles R. Cantor
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Abstract
Streptavidin-metallothionein chimeric proteins with biological recognition specificity in which the streptavidin moiety provides high affinity biotin binding and the metallothionein moiety provides a high affinity metal binding. The binding affinity of the streptavidin-metallothionein chimeric protein both for biotin and heavy metal ions allows specific incorporation into, conjugation with, or labelling of any biological material containing biotin with various heavy metal ions.
Claims7
A recombinant streptavidin-metallothionein chimeric protein having biological recognition specificity.
An expression vector pTSAMT-2 for the streptavidin-metallothionein chimeric protein constructed from an expression vector pTSA-18F for streptavidin-containing chimeric proteins and a mouse metallothionein-I cDNA.
Dependencies are inferred from the claim text.