Mixed cell diagnostic systems
AssigneesDiagnositic Hybrids, Inc., University Hospitals of Cleveland
InventorsDavid R. Scholl, Yung T. Huang, Patricia Gail Ray Goodrum
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Abstract
The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of a organisms to antimicrobial agents.
Claims36
A composition comprising a cell culture suitable for the detection of intracellular parasites, wherein said cell culture comprises at least two cell types and wherein said cell types are susceptible to infection by at least one intracellular parasite.
A method for the detection and identification of intracellular parasites in a sample, comprising the steps of:
- a) providing:
- i) a sample suspected of containing one or more intracellular parasites;
- and
- ii) a mixed cell culture comprising at least two cell types;
- b) inoculating said mixed cell culture with said sample to produce an inoculated culture;
- and
- c) observing said inoculated culture for the presence of said one or more intracellular parasites.
A method for the detection and identification of intracellular parasites in a sample, comprising the steps of:
- a) providing:
- i) a sample suspected of containing one or more intracellular parasites;
- and
- ii) a mixed cell culture comprising a first cell type and a second cell type;
- b) inoculating said mixed cell culture with said sample to produce an inoculated culture;
- and
- c) observing said inoculated culture for the presence of said one or more intracellular parasites.
A method for the detection of influenza virus, comprising the steps of
- a) providing a sample suspected of containing influenza virus, and mink lung cells;
- b) inoculating said mink lung cells with said sample;
- and
- c) detecting the presence of said influenza within said mink lung cells.
Dependencies are inferred from the claim text.