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US 2003/0215531 A1Published application
Compositions and methods of use for extracts of Rutaceae plants
OwnerMartin Stogniew, Walter Chamblissinventors
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OwnerMartin Stogniew, Walter Chamblissinventors
Estimating the term…
The invention relates to compositions and methods for preventing, treating, or managing anxiety, pain, chronic pain, depression, and disorders such as premenstrual syndrome comprising the administration of a prophylactically and therapeutically effective amount of Rutaceae plant or extracts thereof to a mammal in need of such therapy. In a preferred embodiment, the mammal is human and the extracts are substantially free of the compounds obacunone or limonin. The invention also relates to compositions and methods for preventing, treating, or managing separation anxiety in domestic animals comprising the administration of a prophylactically and therapeutically effective amount of Rutaceae plant or extracts thereof to an animal in need of such therapy.
A composition comprising a plant extract substantially free of obacunone and limonin wherein the plant belongs to the family Rutaceae and the composition is suitable for ingestion by a mammal.
An aqueous Rutaceae plant extract substantially free of obacunone and limonin.
A Rutaceae plant extract comprising at least two compounds selected from the group consisting of phellodendrine, magnoflorine, and berberine wherein the Rutaceae plant was extracted using a solvent selected from the group consisting of a lower alcohol, water, or mixtures thereof.
A Rutaceae plant extract obtained by the process of:
A Rutaceae plant extract comprising at least two compounds selected from the group consisting of phellodendrine, magnoflorine, and berberine obtained by extracting a plant of the family Rutaceae with an aqueous organic solution, separating and isolating the solution and reducing solution in volume.
A method for treating or preventing anxiety in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of Rutaceae plant or a composition thereof wherein the Rutaceae plant belongs to the genus Phellodendron, Citrus, Evodia, or Dictamnus.
A method for treating or preventing anxiety in a mammal which comprises administering to a mammal in need of anxiety treatment a therapeutically effective amount of an aqueous Rutaceae plant extract or a composition thereof.
A method for treating or preventing depression in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of a Rutaceae plant or a composition thereof wherein the Rutaceae plant belongs to the genus Phellodendron, Citrus, Evodia, or Dictamnus.
A method for treating or preventing depression in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of an aqueous Rutaceae plant extract or a composition thereof.
A method for treating or preventing pain in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of a Rutaceae plant or a composition thereof wherein the Rutaceae plant belongs to the genus Phellodendron, Citrus, Evodia, or Dictamnus.
A method for treating or preventing pain in a mammal which comprises administering to a mammal in need of pain treatment a therapeutically effective amount of an aqueous Rutaceae plant extract or a composition.
A method for treating or preventing chronic pain in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of a Rutaceae plant or a composition thereof wherein the Rutaceae plant belongs to the genus Phellodendron, Citrus, Evodia, or Dictamnus.
A method for treating or preventing chronic pain in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of an aqueous Rutaceae plant extract or a composition thereof.
A method for treating or preventing premenstrual syndrome in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of a Rutaceae plant or a composition thereof wherein the Rutaceae plant belongs to the genus Phellodendron, Citrus, Evodia, or Dictamnus.
A method for treating or preventing premenstrual syndrome in a mammal which comprises administering to a mammal in need thereof a therapeutically effective amount of an aqueous Rutaceae plant extract or a composition thereof.
A method for treating or preventing separation anxiety for domestic animals which comprises administering to a mammal in need thereof a therapeutically effective amount of a Rutaceae plant extract or a composition thereof wherein the Rutaceae plant belongs to the genus Phellodendron, Citrus, Evodia, or Dictamnus.
A method for treating or preventing a disorder selected from the group consisting of weight loss, cold, appetite loss, sleeplessness, and fatigue which comprises administering to a mammal in need thereof a therapeutically effective amount of a Rutaceae plant extract or a compositions thereof wherein the Rutaceae plant belongs to the genus Phellodendron, Citrus, Evodia, or Dictamnus.
A method for treating or preventing a disorder selected from the group consisting of anxiety, depression, and premenstrual syndrome which comprises administering to a mammal in need thereof a therapeutically effective amount of berberine, a pharmaceutically acceptable salt thereof, or a composition thereof.
A method for treating or preventing a disorder selected from the group consisting of weight loss, cold, appetite loss, sleeplessness, and fatigue which comprises administering to a mammal in need thereof a therapeutically effective amount of berberine, a pharmaceutically acceptable salt thereof, or a composition thereof.
A method for treating or preventing a disorder selected from the group consisting of anxiety, pain, chronic pain, depression, and premenstrual syndrome which comprises administering to a mammal in need thereof a therapeutically effective amount of phellodendrine or magnoflorine, a pharmaceutically acceptable salt thereof, or a composition thereof.
Dependencies are inferred from the claim text.