Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype
AssigneeQueen's University at Kingston
InventorsCharles H. Graham, Lynne-Marie Postovit, Michael A. Adams, Jeremy P.W. Heaton
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Abstract
The present invention relates to methods and formulations for inhibiting, treating and preventing a malignant cell phenotype, cell, tumor and/or disease. Administration of nitric oxide mimetics, such as low doses, is sufficient to increase, restore or maintain nitric oxide-mediated signaling in cells so that malignant cell phenotypes, cells, tumors and/or diseases are inhibited or prevented. These methods and formulations are particularly useful in treating and preventing cancer in animals.
Claims16
A method for controlling, treating and/or preventing cancer, malignancies, neoplasm, hyperplasia, hypertrophy, dysplasia and/or tumor angiogenesis, said method comprising:
- administering a nitric oxide mimetic to an animal thereof, to control, treat and/or prevent said cancer, malignancies, neoplasm, hyperplasia, hypertrophy, dysplasia and/or tumor angiogenesis.
Dependencies are inferred from the claim text.