Dental composition for hypersensitve teeth

A method for preparing a dentifrice composition for reducing dentinal hypersensitivity due to the presence of exposed dentinal surface and open dentinal tubules, comprising a synergistic combination of:

• i) a desensitizing amount of at least two tubule blocking agents, a hydrolysis product of an alternating long chain α-olefin-co-maleic anhydride copolymer as the first blocking agent and an acrylic polymer as the second blocking agent;
• and ii) a nerve desensitizing agent selected from the group consisting of potassium salt, strontium salt, and mixtures thereof, said method comprising:
• a) separately neutralizing the tubule blocking agents by heating them in the presence of a suitable base to form premixes;
• b) combining the two premixes;
• and
• c) forming said dentifrice composition by mixing the combined premixes with said nerve desensitizing agent and conventional dentifrice ingredients.

A method for preparing a dentifrice composition for reducing dentinal hypersensitivity due to the presence of exposed dentinal surface and open dentinal tubules, comprising a synergistic combination of:

• i) a desensitizing amount of at least two tubule blocking agents, a hydrolysis product of an alternating long chain α-olefin-co-maleic anhydride copolymer as the first blocking agent and an acrylic polymer as the second blocking agent;
• and ii) a nerve desensitizing agent selected from the group consisting of potassium salt, strontium salt, and mixtures thereof, said method comprising:
• a) neutralizing said copolymer in an excess of base;
• b) adding said acrylic polymer there under high sheer, thereby neutralizing it with the excess base;
• and
• c) forming said dentifrice composition by mixing the resultant mixture with said nerve desensitizing agent and conventional dentifrice ingredients.