Methods for identifying and monitoring patients at risk for systemic inflammatory conditions, methods for selecting treatments for these patients and apparatus for use in these methods
OwnerGus J. Slotmaninventor
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Abstract
Methods of identifying, monitoring and matching patients with appropriate treatments who are at risk for developing a systemic inflammatory condition prior to development of signs and symptoms using a systemic mediator-associated physiologic test profile are provided.
Claims6
A method for identifying patients who meet clinical entry criteria of a study for a new therapeutic agent for treating a systemic inflammatory condition and who are ready biologically to respond to the new therapeutic agent, said method comprising:
- a) generating a systemic mediator-associated response test profile for a patient, said profile comprising one or more selected patient parameters;
- and
- b) comparing said patient profile with established control profiles for the new therapeutic agent to identify patients who meet clinical entry criteria of the study for the new therapeutic agent and who were ready biologically to respond to the new therapeutic agent.
A method for selecting an effective treatment for a patient at risk for developing a systemic inflammatory condition, said method comprising:
- a) generating a systemic mediator-associated response test profile for a patient, said profile comprising one or more selected patient parameters;
- b) comparing said patient profile with established control profiles for effective treatments to identify an established control profile for an effective treatment similar to said profile;
- and
- c) selecting a treatment for the patient based upon the comparison in step b).
A method for evaluating a patient's risk subclinically for developing a systemic inflammatory condition comprising:
- a) generating a systemic mediator-associated response test profile for a patient, said profile comprising one or more selected patient parameters;
- and
- b) comparing said profile with established control profiles to evaluate the patient's risk subclinically for developing a systemic inflammatory condition based on the comparison.
Dependencies are inferred from the claim text.