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US 2003/0211513 A1Published application
Intracellular signaling proteins
OwnerHenry Yue, Ann He +9inventors
InventorsHenry Yue, Ann He, Danniel B Nguyen, Monique G Yao, Olga Bandman, Neil Burford, Y Tom Tang, Yuming Xu, April J A Hafalia, Yalda Azimzai, Narinder K Chawla
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Abstract
The invention provides human intracellular signaling proteins (ISIGP) and polynucleotides which identify and en code ISIGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ISIGP.
Claims54
An isolated polypeptide selected from the group consisting of:
- a) a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:1-5,
- b) a polypeptide comprising a naturally occurring amino acid sequence at least 90% identical to an amino acid sequence selected from the group consisting of SEQ ID NO:1-5,
- c) a biologically active fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-5, and
- d) an immunogenic fragment of a polypeptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1-5.
1 more element
An isolated polynucleotide selected from the group consisting of:
- a) a polynucleotide comprising a polynucleotide sequence selected from the group consisting of SEQ ID NO:6-10,
- b) a polynucleotide comprising a naturally occurring polynucleotide sequence at least 90% identical to a polynucleotide sequence selected from the group consisting of SEQ ID NO:6-10,
- c) a polynucleotide complementary to a polynucleotide of a),
- d) a polynucleotide complementary to a polynucleotide of b), and
- e) an RNA equivalent of a)-d).
2 more elements
Dependencies are inferred from the claim text.