Microfluidic ion-selective electrode sensor system
AssigneeThe Charles Stark Draper Laboratory, Inc.
InventorsAndrew Dineen, John R. Williams, Jennifer Ryan Prince
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Abstract
Ion-selective electrode sensor systems, and methods of fabricating such systems, may be utilized to analyze microfluidic sample volumes, i.e., sample volumes on the order of 1 to 1000 microliters.
Claims28
An ion-sensor system comprising:
- a sampler assembly comprising:
- a chamber;
- a connector portion;
- and
- an end dimensioned to draw a fluid into the chamber;
- and
- an ion-sensor cartridge comprising:
- an electrical connection portion interconnecting with the sampler assembly connector portion;
- and
- a plurality of ion-selective electrodes.
A method of fabricating an ion-sensor system, the method comprising the steps of:
- providing a substrate;
- forming a plurality of ion-selective electrode regions on the substrate;
- and
- dividing the substrate into a plurality of strips such that each strip contains a plurality of ion-selective electrodes, the strips being electrically connectable to a sampler assembly.
An ion-sensor cartridge for use in a sampler assembly, the sampler assembly comprising a connector portion and an end dimensioned to draw a fluid into a chamber of the sampler assembly, and the ion-sensor cartridge comprising:
- a plurality of ion-selective electrodes;
- and
- an electrical connection portion interconnecting with the sampler assembly connector portion.
A method of measuring one or more electrolytes in blood, the method comprising the steps of:
- extracting blood from a subject;
- transferring the blood to an ion-sensor cartridge comprising an ion-selective electrode;
- and
- analyzing one or more electrolytes in the blood.
Dependencies are inferred from the claim text.