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US 2003/0199964 A1Published application
Drug-polymer coated stents with segmented homochain copolyesters
AssigneePoly-Med, Inc.
InventorsShalaby W. Shalaby, Todd Campbell
Life of this patent
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Abstract
The present invention provides a system for treating a vascular condition, including a catheter, a stent coupled to the catheter, a polymeric coating on the stent including a segmented homochain copolyester, and a bioactive drug dispersed within the polymeric coating.
Claims34
A system for treating a vascular condition, comprising:
- a catheter;
- a stent coupled to the catheter;
- a polymeric coating on the stent, wherein the polymeric coating comprises a segmented homochain copolyester;
- and
- a bioactive drug dispersed within the polymeric coating.
2 more elements
A method of manufacturing a drug-polymer stent comprising:
- mixing a first monomer and a second monomer in a solution;
- reacting the mixture to greater than twenty percent conversion;
- polymerizing the mixture by adding an aliquot of one of the second monomer or a mixture of the second monomer and the first monomer;
- mixing a bioactive agent with the polymerized mixture to form a drug polymer with a predefined elution rate;
- and
- coating a stent with the drug polymer.
3 more elements
A method of manufacturing a drug-polymer stent comprising:
- dissolving a segmented homochain copolyester with a first liquid in a first solution;
- mixing a first bioactive agent in the first solution;
- applying the first solution on a stent to form a primary coat;
- drying the primary coat, wherein the primary coat comprises between 1 percent and 70 percent by weight of the first bioactive agent;
- dissolving a segmented homochain copolyester with a second liquid in a second solution;
- applying the second solution to the stent to form a cap coat;
- and
- drying the cap coat.
5 more elements
A drug-polymer coated stent, comprising:
- a stent including a stent framework;
- and
- a polymeric coating on the stent framework, wherein the polymeric coating comprises a segmented homochain copolyester with an interdispersed bioactive agent.
Dependencies are inferred from the claim text.