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US 2003/0199758 A1Published application
Variable-motion optical tomography of small objects
AssigneeVisiongate, Inc.
InventorAlan C. Nelson
Life of this patent
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AssigneeVisiongate, Inc.
InventorAlan C. Nelson
Estimating the term…
Motion of an object of interest, such as a cell, has a variable velocity that can be varied on a cell-by-cell basis. Cell velocity is controlled in one example by packing cells into a capillary tube, or any other linear substrate that provides optically equivalent 360 degree viewing access, so that the cells are stationary within the capillary tube, but the capillary tube is translated and rotated mechanically through a variable motion optical tomography reconstruction cylinder. The capillary tube motion may advantageously be controlled in a start-and-stop fashion and translated and rotated at any velocity for any motion interval, under the control of a computer program. As such, there are several configurations of the optical tomography system that take advantage of this controlled motion capability. Additionally, the use of polarization filters and phase plates to reduce light scatter and diffraction background noise is described.
A method for three dimensional (3D) reconstruction of an object of interest, comprising the steps of:
A method for three dimensional (3D) reconstruction of an object of interest using a reconstruction cylinder design wherein a plane of point sources and a plane of detector elements are different but parallel, and wherein the reconstruction cylinder has an arrangement of sources and detectors around a circumference of a sample, the method comprising the steps of:
A reconstruction cylinder comprising at least one point source and at least one detector positioned to receive information from the light source, wherein separate projections are created by rotating a sample in the reconstruction cylinder so that light from the at least one light source impinges on the sample forming a projected image on the at least one detector.
A variable-motion optical tomography (VOT) system comprising:
A variable-motion optical tomography (VOT) system comprising:
Any configuration of tomography system where the spaces between the at least one point source and the object and the spaces between the object and the at least one detector surface are filled with a material whose index of refraction is matched with that of the tube.
Dependencies are inferred from the claim text.