Therapeutic anti-cytomegalovirus compounds
AssigneeGenzyme Corporation
InventorCharles A. Nicolette
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Abstract
The present invention provides synthetic compounds, antibodies that recognize and bind to these compounds, polynucleotides that encode these compounds, and immune effector cells raised in response to presentation of these epitopes. The invention further provides methods for inducing an immune response and administering immunotherapy to a subject by delivering the compositions of the invention.
Claims27
A compound having the structure:
- 3
A compound having the structure:
- 4
A compound having the structure:
- 5
A compound having the structure:
- 6
A compound having the structure:
- 7
A compound having the structure:
- 8
A peptide comprising the amino acid sequence of SEQ ID NO:
- 2 wherein amino acids 495, 497 and 500 are F, L and I, respectively.
A peptide comprising the amino acid sequence of SEQ ID NO:
- 2 wherein amino acids 495, 497, 498, 499, 500, 501 and 502 are L, W, D, W, P and F, respectively.
A peptide comprising the amino acid sequence of SEQ ID NO:
- 2 wherein amino acids 495, 497, 498, 499, 500, 501 and 502 are F, F, T, R, F, M and R, respectively.
A peptide comprising the amino acid sequence of SEQ ID NO:
- 2 wherein amino acids 495, 497, 498, 499, 500, 501 and 502 are F, P, H, P, G, W and L, respectively.
A peptide comprising the amino acid sequence of SEQ ID NO:
- 2 wherein amino acids 495, 497, 498, 499, 500, 501 and 502 are F, I, R, L, T, P and P, respectively.
A peptide comprising the amino acid sequence of SEQ ID NO:
- 2 wherein amino acids 495, 497, 498, 499, 500, 501 and 502 are F, D, F, S, F, W and F, respectively.
A polynucleotide that encodes an amino acid sequence comprising the amino acids of SEQ ID NO:
- 3.
A polynucleotide that encodes an amino acid sequence comprising the amino acids of SEQ ID NO:
- 5.
A polynucleotide that encodes an amino acid sequence comprising the amino acids of SEQ ID NO:
- 7.
A polynucleotide that encodes an amino acid sequence comprising the amino acids of SEQ ID NO:
- 9.
A polynucleotide that encodes an amino acid sequence comprising the amino acids of SEQ ID NO:
- 11.
A polynucleotide that encodes an amino acid sequence comprising the amino acids of SEQ ID NO:
- 13.
Dependencies are inferred from the claim text.