Methods for improving efficacy of treatment with growth hormone secretagogues
OwnerDavid A. Fryburg, Ann E. Taylorinventors
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Abstract
The present invention provides methods of increasing efficacy of treatment with growth hormone secretagogues, prodrugs thereof and pharmaceutically acceptable salts of said secretagogues and said prodrugs, for patients who have normal or above normal levels of testosterone. The present invention also provides methods of reducing the therapeutic doses of such compounds in such patients. More specifically, the present invention provides such methods wherein the growth hormone secretagogues are compounds of Formula I: 1 a prodrug thereof or a pharmaceutically acceptable salt of said secretagogue or said prodrug.
Claims17
A method for improving the efficacy of treatment with a growth hormone secretagogue, which comprises administering a therapeutically effective amount of a growth hormone secretagogue to a patient who has normal or above normal testosterone levels.
A method for increasing the effect of a growth hormone secretagogue in a patient, which comprises administering a therapeutically effective amount of a growth hormone secretagogue to a patient who has normal or above normal testosterone levels.
A method for inducing increased anabolic effects in a patient, which comprises administering growth hormone secretagogue to a patient who has, normal or above normal testosterone levels.
A method for reducing the therapeutically effective amount of a growth hormone secretaoguge in a patient, which comprises administering the growth hormone secretagogue to a patient who has normal or above normal testosterone levels.
A method for optimizing treatment with a growth hormone secretagogue, which comprises administering a therapeutically effective amount of a growth hormone secretagogue to a patient who has normal or above normal testosterone levels.
A method for optimizing the response of a patient to treatment with a growth hormone secretagogue, which comprises:
- a) prior to treatment with a growth hormone secretagogue, measuring the testosterone levels of the patient;
- and
- b) if the testosterone levels are below normal for his or her gender, replacing the levels of testosterone in the patient to normal or above normal levels for his or her gender.
Dependencies are inferred from the claim text.