Method for the treatment of urinary incontinence
AssigneeEndo Pharmaceuticals Inc.
InventorFrank S. Caruso
Life of this patent
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Abstract
Urinary incontinence is alleviated in a mammal by administering to the mammal a urinary incontinence alleviating amount of dextromethorphan, dextrorphan, their mixtures and/or pharmaceutically acceptable salts, alone or in combination with a pharmacologically active agent such as an anticholinergic, sympathomimetic, tricyclic antidepressant, antispasmodic, direct-acting smooth muscle relaxant, estrogen, compound having estrogen-like activity, or any combination of the foregoing.
Claims27
A method of treating urinary incontinence which comprises administering to a mammal exhibiting urinary incontinence a urinary incontinence alleviating amount of at least one morphinan selected from the group consisting of dextromethorphan, dextrorphan and pharmaceutically acceptable salts thereof.
A method of decreasing micturition frequency in a mammal which comprises administering to a mammal a micturition decreasing amount of a morphinan selected from the group consisting of dextromethorphan, dextrorphan and pharmaceutically acceptable salts thereof.
A method of treating interstitial cystitis which comprises administering to a mammal exhibiting interstitial cystitis an effective amount of a morphinan selected from the group consisting of dextromethorphan, dextrorphan and pharmaceutically acceptable salts thereof.
A composition comprising at least one morphinan selected from the group consisting of dextromethorphan, dextrorphan and the pharmaceutically acceptable salts thereof and at least one pharmacologically active agent selected from the group consisting of anticholinergics, sympathomimetics, tricyclic antidepressants, antispasmodics, direct-acting bladder smooth muscle relaxants, estrogens, compounds having estrogen-like activity, and any combination of the foregoing.
Dependencies are inferred from the claim text.