Use of ectoin or ectoin derivatives for stabilizing p53
OwnerJoachim Bunger, Francois Marchioinventors
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Abstract
This invention relates to the use of at least one compound, selected from a compound of the formula 1a, 1b, 1 a physiologically compatible salt of it and a stereoisomeric form of it, whereby the following signify R1 H or alkyl, R2 H, COOH, COO-alkyl or CO—NH—R5, R3 and R4 each mutually independent H or OH, n 1, 2 or 3, R5 H, alkyl, an amino acid residue, a dipeptide residue or tripeptide residue, and alkyl an alkyl residue with 1 to 4 carbon atoms, for the stabilisation of p53. According to the invention, these compounds are normally used in the form of a topical composition.
Claims8
Use of at least one compound, selected from a compound with the formula 1a, 1b,
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- a physiologically compatible salt of it and a stereoisomeric form of it, whereby the following signify
- R1 H or alkyl,
- R2 H, COOH, COO-alkyl or CO—NH—R5,
- R3 and R4 each mutually independent H or OH,
- n 1, 2 or 3,
- R5 H, alkyl, an amino acid residue, a dipeptide residue or tripeptide residue, and
- alkyl an alkyl residue with 1 to 4 carbon atoms,
- for the stabilisation of p53.
Dependencies are inferred from the claim text.