Pharmaceutical composition
AssigneeNovartis AG
InventorsBirgit Hauer, Armin Meinzer, Ulrich Posanski, Jacky Vonderscher
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Abstract
Pharmaceutical compositions comprising a cyclosporin in a novel galenic formulations for oral administration. The compositions typically comprise a cyclosporin, 1,2-propylene glycol, a mixed mono-, di- and tri-glyceride and a hydrophilic surfactant. Further a refined glycerol-transesterified corn oil is provided representing a mixed mono-, di- and tri-glyceride suitable for the novel formulation. Dosage forms include in particular oral dosage forms.
Claims30
A pharmaceutical composition comprising a cyclosporin as active ingredient in a carrier medium comprising:
- 1) 1,2-propylene glycol
- 2) a mixed mono-, di-, tri-glyceride, and
- 3) a surfactant.
A composition according to claim l,wherein the carrier medium additionally comprises a hydrophilic phase co-component.
Dependencies are inferred from the claim text.