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US 2003/0199083 A1Published application
Bioreactor with plurality of chambers for conditioning intravascular tissue engineered medical products
AssigneeST3 Development Corporation
InventorsKent Vilendrer, Troy Nickel
Life of this patent
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Abstract
A microprocessor controlled and instrumented bioreactor for conditioning intravascular tissue engineered medical products. One bioreactor design including an integrated pump to provide a relatively small volume of fluid nutrient. The microprocessor control providing measurement and control of the fluid flow and tissue displacement and subsequent determination of material properties. One design includes a flexible joint providing motion of the treated tissue in the axial, bending and torsional direction.
Claims33
A bioreactor for conditioning tissue, comprising:
- a bioreactor chamber, the bioreactor chamber including at least one clamp for holding the tissue;
- circulation means to provide fluid nutrient flow across the surface of the tissue;
- and
- microprocessor control means for measuring fluid flow in the bioreactor chamber and for measuring response of the tissue,
- wherein the microprocessor control means provides real time monitoring and control of conditions for the tissue within the bioreactor chamber.
2 more elements
A bioreactor for treatment of tissue, comprising:
- a plurality of ports;
- a chamber for holding the tissue;
- dynamic pump means for providing dynamic pumping of fluids to the tissue;
- mean pump means for providing a mean flow of fluids to the tissue;
- a first manifold connected to the chamber at one end and a flexible joint connected to the other end;
- a second manifold connected to the flexible joint;
- actuating means for actuating the second manifold with respect to the first manifold;
- sensor means for measuring various pressures and temperatures within the bioreactor;
- and
- control means for controlling fluid flows and motion of the actuating means.
7 more elements
Dependencies are inferred from the claim text.